Our needs-driven technology scouting and commercialisation process is active and strategically driven to serve the bottom of the pyramid. It is a powerful mechanism for building profitable businesses around pro-poor research outputs delivering highly-cost effective, long-term social impact at scale. The enterprises we create increase the household income and reduce the burden of disease experienced by poor people. By unlocking these social returns through commercial enterprises we are able to leverage talented management and later-stage private sector capital focused on driving profitability. This in turn ensures sustainable delivery of social impact and a return on investment that attracts more resources into the commercialisation of socially valuable research outputs.